MicroRNA-183 family conservation and ciliated neurosensory organ expression
نویسندگان
چکیده
منابع مشابه
Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken
The miR-183 family consists of 3 related microRNAs (miR-183, miR-96, miR-182) that are required to complete maturation of primary sensory cells in the mammalian inner ear. Because the level of these microRNAs is not uniform across hair cell subtypes in the murine cochlea, the question arises as to whether hair cell phenotypes are influenced by microRNA expression levels. To address this, we use...
متن کاملExpression and Significance of MicroRNA-183 in Hepatocellular Carcinoma
OBJECTIVE In our previous study, we found that some miRNAs were deregulated in hepatocellular carcinoma (HCC), including miR-183. However, the expression of miR-183 in the progression of benign liver diseases to HCC and its correlation with clinicopathologic factors remain undefined. METHODS MiR-183 expression was measured in normal controls (NC) (n = 21), chronic viral hepatitis B or C (CH) ...
متن کاملSignificance of microRNA-183 family expression in cancer diagnosis: a meta-analysis
Cancer is the third major cause of death in the world and it has turned into an enormous threat to human health. MicroRNAs have been considered as novel and noninvasive biomarkers for human cancer detection. The microRNA-183 (miRNA-183, miR-183) family, consisting of miR-96, miR-182 and miR-183, is considered to be associated with various types of human cancer. However, the diagnostic performan...
متن کاملMicroRNA-183 Family in Inner Ear: Hair Cell Development and Deafness
miRNAs are essential factors of an extensively conserved post-transcriptional process controlling gene expression at mRNA level. Varoius biological processes such as growth and differentiation are regulated by miRNAs. Web of Science and PubMed databases were searched using the Endnote software for the publications about the role miRNA-183 family in inner ear: hair cell development and deafness ...
متن کاملMicroRNA-183 family members regulate sensorineural fates in the inner ear.
Members of the microRNA (miRNA) 183 family (miR-183, miR-96, and miR-182) are expressed abundantly in specific sensory cell types in the eye, nose, and inner ear. In the inner ear, expression is robust in the mechanosensory hair cells and weak in the associated statoacoustic ganglion (SAG) neurons; both cell types can share a common lineage during development. Recently, dominant-progressive hea...
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ژورنال
عنوان ژورنال: Evolution & Development
سال: 2008
ISSN: 1520-541X
DOI: 10.1111/j.1525-142x.2007.00217.x